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1. What is Ephedrine and what is it used for?
Ephedrine belongs to a group of medicines called sympathomimetics.
Sympathomimetics act on the part of the nervous system that controls automatic functions.
Ephedrine is used to treat low blood pressure during spinal cord injection
counteract. Ephedrine raises blood pressure by temporarily reducing blood flow to the small one
Reduced blood vessels.

2. What should you watch out for before giving Ephedrine?
Ephedrine must not be used
– if you are allergic (hypersensitive) to ephedrine hydrochloride or any of the substances mentioned in section 6.
ingredients of this medicine
– if you have hyperthyroidism, appetite increase, weight loss or sweating
can cause
– if you have an enlarged prostate
– if you have heart disease
– if you have an increased intraocular pressure (glaucoma)
– if you have diabetes mellitus
– if you have a thrombosis
– if you have low blood pressure
– if you are taking MAO inhibitors (monoamine oxidase inhibitors) (see application of
Ephedrine with other medicines)
– if you have high blood pressure.
If any of the above applies to you, please inform your doctor.

Use of ephedrine with other medicines
Please inform your doctor or nurse if you are taking any other medicines
ingest / use or have recently taken / used, even if it is not
prescription medicines.
Other medicines that may interact with ephedrine  include:
– a certain type of antidepressants called MAO inhibitors (monoamine oxidase inhibitors)
become. Tell your doctor or nurse, even if
You have stopped taking a MAO inhibitor in the last two weeks;
– cough and cold remedies;
– Narcotics for inhalation, such as halothane;
– medicines for the treatment of depression;
– sibutramine, an appetite suppressant;
– linezolid, a medicine used to treat infections;
– medicines for the treatment of bronchial asthma such as theophylline;
– Corticosteroids, a group of medicines used in different diseases
To reduce swelling;
– medicines for epilepsy;
– Doxapram, a drug used to treat respiratory problems;
Oxytocin, a medicinal product used in childbirth;
– Medicines for the treatment of hypertension such as guanethidine.
pregnancy and breast feeding period
If you are pregnant or breastfeeding, or suspect you may be pregnant or intend to
To get pregnant, ask your doctor for advice before being given this medicine.
Driving and using machines
Ephedrine  will not affect the ability to drive or to drive
Machines expected. However, if you feel unwell, first ask your doctor before returning
start to drive a vehicle or operate machinery.
laboratory tests
This medicine contains an active substance that may give positive results in doping controls.

3. How to administer Ephedrine?
This is a medicine for injection that is given to you by your doctor. Your doctor will too
Determine the dose you need.

Adult and older patients:
The usual starting dose is 3-7.5 mg as a slow injection into a vein. The injection will be yours
may be repeated once or several times until you reach the maximum dose of the drug (30 mg)
have received.
Patients with kidney or liver dysfunction:
There are no special dosage recommendations for patients with kidney or kidney dysfunction

Ephedrine  30 mg / ml, concentrate for solution for injection, is not recommended for
Use in children due to inadequate safety and safety data and Dosage recommendations.

If you suspect you have received too much Ephedrine
This medicine will be given to you by your doctor and therefore it is unlikely that you will
much of it received. Your doctor is aware of how an overdose is detected and treated.
If you are worried about your treatment, talk to your doctor.
If you have any further questions on the use of the medicine, contact your doctor or the
medical professionals.

4. What side effects are possible?
Like all medicines, ephedrine  may cause side effects, although not everybody gets them
have to.

– confusion, concern, depression
– nervousness, irritability, restlessness, weakness, insomnia, headache, sweating, anxiety
– Increased perception of the heartbeat (palpitations), high blood pressure, rapid heartbeat
– shortness of breath
– nausea, vomiting.
– Irregular heartbeat
– Problems urinating.
Other side effects (how often these are not known):
– influence on blood clotting
– allergy
– Changes in personality or emotional or mental world, fear
– tremors, excessive salivation
– increased pressure in the eye (glaucoma)
– Pain over the heart, slow heartbeat, heart failure (cardiac arrest), lower
blood pressure
– Bleeding in the brain
– breathing problems
– Appetite reduction
– decrease in potassium content in the blood, change in blood sugar levels
– Fluid accumulation in the lungs (pulmonary edema).

Overdose with this medicine may cause you to:
– see or hear things that are not there (hallucinations)
– believe things that do not apply (delusions)
– notice changes in your personality or your emotional or mental world.
If you notice any side effects, consult your doctor or nurse.
This also applies to side effects not listed.

5. How to store Ephedrine?
Keep this medicine out of the sight and reach of children.
This medicine may be given after the label and the carton after “EXP” respectively
“Usable until” specified expiration date can no longer be administered. The expiry date relates
on the last day of the given month.
This medicinal product does not require special storage conditions.

Do not dispose of medicines in wastewater. Ask your pharmacist how to take the medicine
dispose of when you stop using it. You help to protect our environment.

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1. What is Testosterone?

Testosterone first appeared in the U.S. prescription drug market during the early 1950’s, as Delatestryl by Squibb.  It changed hands several times over the years, most notably to Mead Johnson, BTG, Savient, and in December 2005, Indevus. Testosterone is the primary androgen found in the body. Endogenous testosterone is synthesized by cells in the testis, ovary, and adrenal cortex. Therapeutically, testosterone is used in the management of hypogonadism, either congenital or acquired. Testosterone is also the most effective exogenous androgen for the palliative treatment of carcinoma of the breast in postmenopausal women.

The Testosterone benefits are nothing short of perfect and certainly nothing short of amazing. Through the use of Testosterone Enanthate we create a perfect environment apt for bringing forth the attributes of increased muscle mass and strength, as well as an improved metabolic rate due to the increase in tissue as well as the steroids control over fat promoting hormones. Further, because testosterone is imperative to repair and recovery after intense activity, when our levels are increased through the use of Testosterone we readily speed this process up as well as give it greater efficiency.

Except above testosterone benefits, Testosterone is the perfect remedy for treating low testosterone. If you suffer from low testosterone, this simply means your body is no longer producing enough of this primary androgen on its own. As Testosterone Enanthate is simply that, testosterone, it will remedy the low level condition. Millions upon millions of men worldwide suffer from some type of low level androgen deficiency. In the U.S. alone it is estimated that more than 20 million men suffer from an androgen deficiency. Women can also suffer from low testosterone and Testosterone Enanthate can treat it. However, most women will be better served with alternative forms of testosterone treatment such as gels that contain a mixture of testosterone and progesterone or small testosterone implant pellets like Testopel

3. Testosterone enanthate dosage?

Testosterone is for injection into a muscle. Testosterone Enanthate is usually employed in a higher testosterone dosage (usually a minimum of 500mg per week).

Medically, Testosterone is usually utilized at a prescription dosage of around 250mg, depending on the discretion of the physician and the patient’s progress in his TRT therapy.

For the purpose of bodybuilding and performance and physique enhancement, Testosterone is usually dosed at around 300 – 500mg per week as a beginner testosterone dosage. Intermediate Testosterone dosages can run from 500 – 750mg per week, and advanced users are known to utilize upwards of 1,000mg or more per week of Testosteron.

4. Testosterone enanthate side effects

Testosterone is an anabolic steroid with a very moderate side effect profile. When considering testosterone benefits in terms of potential gains and strength versus its side effect potential and profile, it can be considered a very reasonable anabolic steroid in this regard. Testosterone Enanthate’s side effect distribution is generally pretty varied, but what one must understand is that Testosterone Enanthate being a Testosterone compound, is the body’s most natural anabolic hormone. After all, Testosterone is what the body endogenously manufactures naturally and it is therefore what the body is most accustomed to first and foremost. As with any side effects of any sort, individual body reaction, sensitivity, and genetics play a large factor in whether or not an individual may experience more or less of a certain side effect (or experience none at all).

Testosterone side effects include that of estrogenic side effects, which are the most prominent testosterone enanthate side effects that users and potential users are most concerned about. This results from the fact that Testosterone is a moderately aromatizable anabolic steroid (meaning Testosterone undergoes conversion into Estrogen at a moderate rate in the body), and this is of course proportional to the dose of Testosterone Enanthate used as well. The greater the dosage, the greater the degree of aromatization into Estrogen. The resultant side effects of Estrogen conversion can include: water retention and bloating, increases in blood pressure (resultant from water retention), increased fat gain/retention, and potential development of gynecomastia.

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In 70 percent of cases, physical causes are responsible for erectile dysfunction. Most often, penile blood circulation is disturbed and / or the penile gland itself, which is very similar to the vascular wall musculature, falls ill. Either too little blood in the penis arrives because the supplying arteries are “calcified” (arteriosclerosis). Or the blood drains off too quickly through the veins. Or both. In any case, the amount of blood in the erectile tissue of the penis is no longer sufficient for a satisfactory erection.

Circulatory disorders

Various diseases that promote circulatory disorders also increase the risk of erectile dysfunction: Diabetes mellitus (diabetes), hypertension, lipid metabolism disorders. The lifestyle also has a decisive influence: Smoking, obesity, physical inactivity and a one-sided and unhealthy diet increase the blood vessels and thus increase the probability of potency problems. Conversely, a healthy lifestyle helps to prevent potency disorders. It has also been shown repeatedly that a healthy lifestyle and regular exercise exercise a favorable influence on an erectile dysfunction. Erectile dysfunction is often the first warning sign of vascular disease and thus a possible harbinger from heart attack or stroke. If atherosclerosis is detected and treated early, Often bad consequences can be avoided. Not least for this reason, it is advisable to clarify a potency problems medically.

Testosterone deficiency

The male sex hormone testosterone seems to have a significantly greater impact on the love life as long suspected. This is shown by recent research results. So is a sufficiently high hormone level apparently a very important condition for a satisfactory erection. With the years of life, testosterone levels in the blood usually fall off in men. A testosterone deficiency (hypogonadism) does not have, but may well lead to impotence. Therefore, if men have erection problems, they should necessarily also have low testosterone levels as a possible cause be considered.

Drug side effects

Important to know: Many medications can cause impotence as a side effect, including beta-blockers for high blood pressure, dehydrating medications, lipid-lowering drugs or depression medications. If there is an indication in the instruction leaflet and there is a suspicion that the remedy might be a cause of erectile dysfunction, patients should consult their physician. Maybe he can prescribe another drug. Caution: Do not discontinue or change medication on your own!

Other causes

For an erection to come, not only the penis circulation must be right. All involved nerve tracts – from the penis to the spinal cord to the brain – must be intact. Herniated discs, injuries, radiation or pelvic or spinal cord surgery can cause erectile dysfunction. Also, diseases that can cause damage to peripheral nerves (a neuropathy) – such as diabetes mellitus (diabetes) or chronic alcohol abuse. Other possible causes of erectile dysfunction include diseases affecting the central nervous system, such as multiple sclerosis, Parkinson’s disease, Alzheimer’s disease or stroke. Serious diseases – such as cancer, severe kidney or liver disease – can always affect the potency with.

Psychic triggers

Physical and emotional triggers can be mixed in erectile dysfunction. If men suffer from physical problems with potency, they easily develop additional psychological problems. Purely psychologically caused causes can be found especially in younger men. In addition to conflicts in the partnership, stress, problems or anxiety disorders, depression is very often with associated with erectile dysfunction. In erectile dysfunction, the man can not get or maintain an erection sufficient for intercourse. The penis does not get hard enough and / or recovers quickly. The problems last for at least six months and occur in more than two-thirds of the cases. Often, erectile dysfunction (commonly called “impotence”) gradually develops and occurs both in intercourse with the partner and in masturbation. This constellation indicates physical causes such as vascular changes (see chapter Causes). In every healthy man, erections occur in certain phases of sleep. If they stay out, this is another indication of physical causes. Does it only in very specific situations to erectile dysfunction and they are very sudden – almost from one day to the other – are the possible (but not proving) signs of psychic trigger.

Balance testosterone deficiency

With increasing age, the testosterone level in the blood drops slightly in almost all men. This is nothing unusual and no reason for a therapy. However, if a man suffers from erectile problems, a testosterone deficiency (hypogonadism) could play a decisive role. In this case, the doctor will advise to balance the hormone deficiency. Maybe this will already improve the potency problems. Often, erectile dysfunction medications (PDE-5 inhibitors, see below) are better or first in combination with hormone therapy. Some men with erectile dysfunction even benefit from testosterone supplements, although her blood levels are actually in a near normal range. When does the hormone supplement make sense? It should therefore be decided individually – jointly by doctor and patient. The testosterone is applied in the form of a gel on the skin or sprayed at greater intervals in the muscle. At first, research seemed to indicate that That a testosterone therapy could possibly increase the risk for prostate cancer or a heart attack. However, according to current knowledge such fears are unfounded, say experts – a professional medical treatment provided. Mostly, however, only the symptoms, not the actual triggers of erectile dysfunction can be treated. There are various options, from medication to mechanical aids. What helps best in an individual case is an individual decision the after extensive consultation on possible side effects and risks together with the doctor – and ideally, of course, together with the partner – should be taken. Patients themselves can help to maintain or even improve their potency for a long time. What keeps the blood vessels fit also prevents erectile dysfunction. In detail this means: Do not smoke, eat well, drink little alcohol, move a lot, lose weight, blood pressure, Check blood sugar and blood lipids regularly and treat them with bad results.


In Germany, various phosphodiesterase 5 inhibitors (PDE-5 inhibitors) are approved for the treatment of erectile dysfunction: the first was sildenafil, which was launched in 1998. Tadalafil, Vardenafil and Avanafil followed. All are prescription. Effect and side effects are roughly comparable. The tablets help about 70 to 80 percent of “impotent” men and differ mainly in dosage and duration of action. Sildenafil, vardenafil and avanafil work after about 15 to 60 minutes (the onset of effect may be delayed after high-fat meals). Their effect lasts around four to twelve hours. Tadalafil works after about 30 minutes for about 24 to 36 hours. This medication can also be prescribed as a permanent medication with one tablet a day. As the name suggests, the drugs inhibit phosphodiesterase-5 (PDE-5), which is an endogenous enzyme. This enzyme normally breaks down a certain messenger substance, which increases in sexual arousal and increases blood circulation in the penis. If the enzyme phosphodiesterase-5 is now obstructed in its work by the drugs, there is more messenger left. Consequently, penile blood flow increases, an erection develops or persists longer. A second effect is that the blood pressure in the pulmonary circulation drops. Phosphodiesterase 5 inhibitors are therefore also used to treat pulmonary hypertension. PDE-5 inhibitors only work if the man is sexually aroused. So you do not increase the desire. The erection ends – as without medication – with orgasm or ejaculation. Within the duration of action, however, further erections are possible. Possible side effects include headache, facial flushing, heartburn, stuffy nose, Transient changes in color vision in sildenafil and vardenafil, in Tadalafil also muscle and back pain. Exact information can be found in the leaflet. Not suitable are PDE-5 inhibitors for patients prescribed by the doctor nitrates or molsidomine, because it can lead to a dangerous drop in blood pressure here. Nitrates or molsidomine, for example, in the treatment of angina pectoris in coronary Heart disease used. Some diseases (for example, severe liver disease, Heart disease or a stroke in the past) may speak against taking PDE-5 inhibitors. The PDE-5 inhibitors are good for a prescription. Before the first application, patients should consult the doctor extensively on side effects and inform possible individual risks. Another drug for the treatment of erectile dysfunction is yohimbine, which acts in the brain and especially for psychically induced potency disorders is used.

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Steroids for injection

Steroids inject.

Buy steroids for intramuscular injection like Testosterone, Sustanon, Parabolan, Primobolan, Winstrol and many more.

Overview of Steroids

Anabolic steroids are synthetically produced variants of the naturally occurring male hormone testosterone that are abused in an attempt to promote muscle growth, enhance athletic or other
physical performance, and improve physical appearance. Testosterone, nandrolone, stanozolol, methandienone, and boldenone are some of the most frequently abused anabolic steroids.

Street names of Steroids inject

Arnolds, Juice, Pumpers, Roids, Stackers, Weight Gainer

Steroids look like

Steroids are available in: tablets and capsules, sublingual-tablets, liquid drops, gels, creams, transdermal patches, subdermal implant pellets, and water-based and oil-based injectable solutions. The appearance of these products varies depending on the type and manufacturer.

Methods of abuse of Steroids inject

Steroids are ingested orally, injected intramuscularly, or applied to the skin. The doses abused are often 10 to 100 times higher than the approved therapeutic and medical treatment dosages. Users typically take two or more anabolic steroids at the same time in a cyclic manner, believing that this will improve their effectiveness and minimize the adverse effects.

Affect on mind of Steroids

Case studies and scientific research indicate that high doses of anabolic steroids may cause mood and behavioral effects. In some individuals, steroid use can cause dramatic mood swings, increased feelings of hostility, impaired judgment, and increased levels of aggression (often referred to as “roid rage”). When users stop taking steroids, they may experience depression that may be severe enough to lead one to commit suicide. Anabolic steroid use may also cause psychological dependence and addiction.

Affect on body from Steroids inject

A wide range of adverse effects is associated with the use or abuse of anabolic steroids. These effects depend on several factors including: age, sex, the anabolic steroid used, amount used, and duration of use. In adolescents, anabolic steroid use can stunt the ultimate height that an individual achieves. In boys, steroid use can cause early sexual development, acne, and stunted growth. In adolescent girls and women, anabolic steroid use can induce permanent physical changes, such as deepening of the voice, increased facial and body hair growth, menstrual irregularities, male pattern baldness, and lengthening of the clitoris. In men, anabolic steroid use can cause shrinkage of the testicles, reduced sperm count, enlargement of the male breast tissue, sterility, and an increased risk of prostate
cancer. In both men and women, anabolic steroid use can cause high cholesterol levels, which may increase the risk of coronary artery disease, strokes, and heart attacks. Anabolic steroid use can also cause acne and fluid retention. Oral preparations of anabolic steroids, in particular, can damage the liver. Abusers who inject steroids run the risk of contracting various infections due to non-sterile injection techniques, sharing of contaminated needles, and the use of steroid preparations manufactured in non-sterile environments. All these factors put users at risk for contracting viral
infections such as HIV/AIDS or hepatitis B or C, and bacterial infections at the sight of injection. Abusers may also develop endocarditis, a bacterial infection that causes a potentially fatal inflammation of the heart lining.

Drugs causing similar effects of Steroids

There are several substances that produce effects similar to those of anabolic steroids. These include human growth hormone (hHG), clenbuterol, gonadotropins, and erythropoietin.

Affect on body of Steroids

A wide range of adverse effects is associated with the use or abuse of anabolic steroids. These effects depend on several factors including: age, sex, the anabolic steroid used, amount used, and duration of use. In adolescents, anabolic steroid use can stunt the ultimate height that an individual achieves. In boys, steroid use can cause early sexual development, acne, and stunted growth. In adolescent girls and women, anabolic steroid use can induce permanent physical changes, such as deepening of the voice, increased facial and body hair growth, menstrual irregularities, male pattern baldness, and lengthening of the clitoris. In men, anabolic steroid use can cause shrinkage of the testicles, reduced sperm count, enlargement of the male breast tissue, sterility, and an increased risk of prostate
cancer. In both men and women, anabolic steroid use can cause high cholesterol levels, which may increase the risk of coronary artery disease, strokes, and heart attacks. Anabolic steroid use can also cause acne and fluid retention. Oral preparations of anabolic steroids, in particular, can damage the liver. Abusers who inject steroids run the risk of contracting various infections due to non-sterile injection techniques, sharing of contaminated needles, and the use of steroid preparations manufactured in non-sterile environments. All these factors put users at risk for contracting viral
infections such as HIV/AIDS or hepatitis B or C, and bacterial infections at the sight of injection. Abusers may also develop endocarditis, a bacterial infection that causes a potentially fatal inflammation of the heart lining.

Overdose effects of Steroids inject

Anabolic steroids are not associated with overdoses. The adverse effects a user would experience develop from the use
of steroids over time.

Common places of origin of steroids

Most illicit steroids are smuggled into the U.S. from abroad. Steroids are also illegally diverted from legitimate sources (theft or inappropriate prescribing). The Internet is the most widely used means of buying and selling anabolic steroids. Steroids are also bought and sold at gyms, bodybuilding competitions, and schools from teammates, coaches, and trainers.

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1. What are Tramadol and what is it used for?

Tramadol hydrochloride – the active ingredient in Tramadol – is an analgesic (analgesic) from the group of opioids, which acts on the central nervous system. Its pain relief reaches it by its effect on certain nerve cells of the spinal cord and the brain.

Tramadol are used to treat moderate to severe pain.

2. What should you watch out for before taking Tramadol?

Tramadol should not be taken,

If you are allergic to tramadol hydrochloride or any of the other ingredients of this medicine (listed in section 6).
in acute poisoning with alcohol, sleeping pills, analgesics or other psychotropic drugs (drugs with effects on mood and emotional life).
if you are taking MAO inhibitors (medicines to treat depression) or if you have taken drops within the last 14 days prior to treatment with Tramal (see “Taking Tramadol with other medicines”).
if you have epilepsy and your seizures can not be adequately controlled by treatment.
as a substitute for drug withdrawal.

Warnings and Precautions:

Please talk to your doctor or pharmacist before you use Tramadol,

if you think you are dependent on other painkillers (opioids) or have already been sensitive to opioids in the past.
if you have a mental disorder (if you feel close to fainting).
when you are in shock (cold sweat may be an indication).
if you have conditions with increased intracranial pressure (possibly after a head injury or brain disease).
if you have difficulty breathing.
if you are prone to epilepsy or seizures.
if you have liver or kidney problems.

Epileptic seizures have been reported in patients taking tramadol at the recommended dose. The risk could increase if the recommended maximum daily dose (400 mg) is exceeded.

Please note that Tramadol can lead to a physical and emotional dependence. With prolonged use, the effect of Tramadol may decrease, so that higher doses (amounts of the drug) must be taken (tolerance development). Patients who are prone to drug abuse or have drug dependence should therefore only receive Tramal treatment at short notice and under the strictest medical supervision.

If a patient discontinues tramadol therapy, especially after prolonged use, a gradual dose reduction is recommended to avoid withdrawal symptoms.

Please also tell your doctor if any of these problems occur while you are taking Tramadol, or if this information was previously available to you.

Taking Tramadol with other medicines

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Tramadol should not be taken with MAO inhibitors (certain medicines used to treat depression).

The analgesic effect of Tramadol can be reduced and the duration of action shortened if you take medicines containing any of the following active ingredients.

Carbamazepine (for epileptic seizures)
Ondansetron (for nausea)

Your doctor will tell you if and if so in what dosage Tramadol may be taken.

The risk of side effects increases when you

Tramadol and sedatives, hypnotics, other painkillers such as Take morphine or codeine (also cough medicine) and alcohol. They may feel drowsy or feel close to fainting. If this happens, please inform your doctor.
Taking medicines that can cause seizures (seizures), such as certain antidepressants or antipsychotics (medicines that affect the consciousness). The risk of having a seizure may be increased if you take Tramal retard. Your doctor will tell you if Tramal retard is right for you.
take certain antidepressants (medicines for depression). Tramal retard may interact with this medicine and you may experience symptoms such as involuntary, rhythmic muscle contractions, including muscle, which control the movement of the eyes, restlessness, excessive sweating, tremors, exaggerated reflexes, increase in muscle tension, body temperature above 38 ° C feel.
concomitantly with Tramadol coumarin anticoagulants (medicines for blood thinning), e.g. Warfarin. The effect of these medicines on blood coagulation may be affected and bleeding may occur.

Taking Tramadol along with food and alcohol

Do not drink alcohol during treatment with Tramadol, as its effects may be increased. Foods do not affect Tramadol.

Pregnancy, breast-feeding and fertility

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

There is limited information on the safety of tramadol hydrochloride in pregnancy. Therefore, you should not take Tramadol during pregnancy.

Prolonged use during pregnancy may lead to withdrawal symptoms in the newborn (the neonate may experience a change in the respiratory rate).

Your doctor will therefore only prescribe Tramadol during pregnancy if you have to.

Taking tramadol hydrochloride while breast-feeding is generally not recommended. Tramadol hydrochloride is excreted in breast milk in very small amounts. With a single dose, an interruption of breastfeeding is usually not required.
Procreation / childbearing

Based on human experience, tramadol does not affect female or male fertility.
Driving and using machines

CAUTION: This medicine may affect the ability to react and to drive!

Traminal drops can cause drowsiness, dizziness, and blurred vision, and affect your ability to react. If you feel that your responsiveness is impaired, do not drive a car or other vehicle, do not operate electrical tools or machinery.
Tramadol contains sucrose and macrogolglycerol hydroxystearate

If your doctor has told you that you have an intolerance to certain sugars, ask your doctor for advice before taking Tramadol, as the tablets contain sucrose. If Tramadol are intended for chronic use (i.e., for two weeks or longer), they could be detrimental to the teeth.

Tramadol contain macrogolglycerol hydroxystearate, a derivative of castor oil that can cause stomach upset and diarrhea.

3. How to take Tramadol?

Always take this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are not sure.

The dose should be adjusted to the intensity of your pain and to your individual pain sensation. In general, the smallest possible dose, with which freedom from pain is achieved, should be taken.

Do not take more than 160 drops (for example, 8 times 20 drops) (equivalent to 400 mg tramadol hydrochloride) daily, unless your doctor has ordered it accordingly.

Unless otherwise prescribed by the doctor, the usual dose is:
Adults and adolescents from 12 years

The usual dose of Tramadol in the dropper bottle is 20 to 40 drops (equivalent to 50 to 100 mg of tramadol hydrochloride).

The effect lasts about 4 to 8 hours, depending on the intensity of the pain.

For moderately severe pain, 50 mg tramadol hydrochloride (20 drops) should be administered. If there is no adequate pain relief within 30 to 60 minutes, another 50 mg can be administered. For severe pain conditions, 100 mg tramadol hydrochloride (40 drops) may be given as an initial dose.
Children from 1 year

The usual single dose Tramadol in the dropper bottle for infants from 1 year of age with the dropper is 4 to 8 drops per 10 kg of body weight (corresponding to about 1-2 mg of tramadol hydrochloride per kg of body weight). You will find detailed information about the body weight dose at the end of this leaflet.

In general, the lowest effective dose is chosen to achieve freedom from pain.

Daily doses of 8 mg tramadol hydrochloride per kg body weight or 400 mg tramadol hydrochloride (whichever is lower) should not be exceeded.

For the use of Tramadol in children it is recommended to administer the solution by means of a dropper bottle and not with the aid of a bottle with a dosing pump in order to allow an exact body weight related dosage.
Elderly patients

In elderly patients (over 75 years), excretion of tramadol hydrochloride may be delayed. If this applies to you, your doctor may recommend that you prolong the dose interval.

Severe liver or kidney disease (insufficiency) / dialysis patients

If you have liver and / or kidney failure, your doctor may recommend prolonging the dose interval.
How and when should you take Tramadol?

Oral drops (for oral use).

Take the drops with some liquid or on a sugar cube. A detailed description of the use of the dropper bottle can be found at the end of this leaflet. You can take Tramadol on an empty stomach or with a meal.
How long should you take Tramadol?

You should not take Tramadol for longer than absolutely necessary. If, depending on the type and severity of the disease, a longer lasting pain treatment seems to be necessary, your doctor will check at regular intervals (possibly by taking breaks), if you should continue to use Tramadol and if so in which dose.

Please talk to your doctor or pharmacist if you think the effects of Tramadol are too strong or too weak.
If you take more Tramadol than you should

Inadvertently, if you accidentally take an additional dose of Tramadol, it will not have a negative effect. Further intake of Tramadol should be made as prescribed.

Ingestion of very high doses can lead to narrow pupils, vomiting, drop in blood pressure, accelerated heartbeat, circulatory collapse, impaired consciousness, even coma (deep unconsciousness), epileptiform seizures and difficulty breathing, including respiratory arrest. Immediately call a doctor for help when these signs appear!
If you forget to take Tramadol

If you forget to take Tramadol, your pain may recur. Do not take the double dose, but continue as before.
If you stop taking Tramadol

If you stop treatment with Tramadol or stop prematurely, this will lead to a recurrence of the pain. If you would like to discontinue the treatment because of unpleasant side effects, please contact your doctor.

In general, stopping treatment with Tramadol will have no after-effects. In rare cases, however, patients treated with Tramadol for extended periods of time may feel uncomfortable when treatment is stopped abruptly. You may feel restless, anxious, nervous or shaky. You may be hyperactive, have difficulty sleeping or have gastrointestinal discomfort. Very few people may experience panic attacks, cognitive disorders, abnormalities such as itching, tingling and numbness and tinnitus. Other unusual disorders affecting the central nervous system, such as Confusion, delusions, disturbance of the ego experience (depersonalization), disturbance in the perception of reality (derealization) and persecution mania (paranoia) were observed very rarely. If any of these symptoms occur after stopping treatment, contact your doctor.

If you have any further questions on the use of the medicine, ask your doctor or pharmacist.

4. What side effects are possible from tramadol?

Like all medicines, this medicine can cause side effects, although not everybody gets them.

You should see a doctor immediately if you experience symptoms of an allergic reaction such as swelling of the face, tongue and / or throat and / or difficulty in swallowing or rash with concomitant breathing difficulties.

The most common side effects that occur during treatment with Tramadol are nausea and dizziness, which is more common than in 1 in 10 people.
Very common: may affect more than 1 in 10 people


Frequently: can affect up to 1 in 10 people

Headache, drowsiness
Constipation, dry mouth, vomiting
Sweating (hyperhidrosis)

Uncommon: may affect up to 1 in 100 people

Influencing the heart activity (palpitations, increased heartbeat). These side effects can occur especially with upright posture and physical stress.
Nausea, stomach discomfort (eg stomach pressure, feeling of fullness), diarrhea
Skin reactions (eg itching, rash)

Rarely: can affect up to 1 in 1000 people

allergic reactions (e.g., difficulty breathing, wheezing, swelling of the skin) and shock (sudden circulatory failure) have occurred in very rare cases
Slowed heartbeat
Increase in blood pressure
Misbehavior (such as itching, tingling sensation, numbness), trembling, epileptic seizures, muscle twitching, coordination disorders, temporary loss of consciousness (fainting), speech disorders
Epileptic seizures occurred predominantly after administration of high doses of tramadol or when tramadol is taken concomitantly with drugs that cause seizures.
appetite changes
Perception disorders (hallucinations), confusion, sleep disorders, delirium, anxiety and nightmares
Mental complaints may occur after treatment with Tramal, with their intensity and nature varying in individual ways (depending on the patient’s personality and duration of use). These may be mood changes (usually elevated, occasionally irritable mood), changes in activity (usually attenuation, occasional increase) and reduction in cognitive and sensory performance (change in sensory perception and cognition, which can lead to errors in decision-making behavior) ,
A dependency can occur. If Tramadol are taken over a longer period of time, drug dependency may develop, although the risk is low. With abrupt discontinuation of the drug withdrawal reactions may occur (see “If you stop using Tramadol”).
Blurred vision, narrowing of the pupils (miosis), strong pupillary dilation (mydriasis)
Reduction of breathing, shortness of breath (dyspnoea)
An exacerbation of asthma has been reported, but a link with the drug tramadol hydrochloride could not be established. Exceeding the recommended doses or using other medicines that act to depress the brain at the same time may result in decreased breathing.
Decreased muscle power
Difficult or painful urination or less urine than normal (dysuria)

Very rare: may affect up to 1 in 10,000 people

Increase in liver enzyme levels

5. How to store Tramadol?

Tramadol are stable after opening at 25 ° C – 30 ° C until the expiry date stated.

Keep this medicine out of the sight and reach of children!

Do not use this medicine after the expiry date which is stated on the carton and the glass bottle label. The expiry date refers to the last day of the specified month.

Do not dispose of medicines in wastewater or household waste. Ask your pharmacist how to dispose of the medicine when you stop using it. You help to protect our environment.

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What are SARMs?

Sarms – Selective modulators of androgen receptors, which were designed to replace a variety of anabolic steroids with their rich bouquet of various side effects for the body. These drugs can safely be called a new solution for those who do not want to resort to “strong chemistry”, and wants to simply increase quality meat and become more powerful without any side effects. The main advantage is that during their development all the achievements and advantages of predecessors were used. But there is more. Earlier we have said that modern medicine makes a strong emphasis on safety. And this vector completely passed through SARMs, because at the creation of these drugs researchers focused on reducing the adverse effects of the main male hormone-testosterone on the prostate.

How do SARMs work?

The principle of their functioning is very simple – SARMs join the receptors of male sex hormones and interact with them directly. In fact, the positive effects of these additives on the growth of muscle mass and strength indicators became known at all recently. However, the fame of efficiency and, most importantly, the safety of these pharmacological means with the speed of sound flew through the bodybuilder series, which served as a stimulus to the active use of SARMs in the big sport.

Note that nowadays many pharmaceutical companies already have on hand some types of these drugs that have successfully overcome a number of different clinical studies in humans. What exactly-we will consider next.

The word MSAR (SARM) stands for “Selective androgen receptor modulator”, like other selective receptor modulators, SARMs can either block or stimulate, hormone receptors in the nucleus of the cell depending on Focus of their actions. Consequently, they can block or stimulate receptors in the body tissues selectively, simulating a beneficial effect in one tissue, and at the same time minimizing the unwanted effects of synthetic steroid hormones in other tissues. SARMs belong to the class of androgens (a specific class of hormones, which are produced by sexual glands, one of these hormones-is known to all testosterone). SARMs can be attached to the androgen receptors in the cell, resulting in a complex process of activating certain genes responsible for muscle hypertrophy, regeneration of bone and connective tissues.

In fact, anabolic androgenic steroids (AAS) and prohormones are also associated with androgen receptors, resulting in muscle growth. However, SARMs show their anabolic activity only in muscle and bone tissue, and have minimal impact on other tissues and in the body, such as on prostate, as opposed to AAs, which can be very harmful to this gland. As an added benefit, SARMs is used orally rather than injected, unlike most of the AAS.

Despite the fact that SARMs are produced in oral form, they are not toxic to the liver.

Due to the fact that SARMs are very selective on action on androgen receptors only in certain tissues of the body, they can be very useful for building excellent muscle mass without side effects. Also SARMs are not converted into estrogens, unlike AAs, which, of course, is their distinctive feature and a huge advantage.

Steroids are usually prescribed by doctors in two cases. The first is to treat muscular atrophy caused by serious diseases such as cancer or osteoporosis. The second case is the appointment of steroids as hormone therapy (HRT). However, the main problem of steroids is that they almost always cause a lot of side, undesirable effects.

Scientists decided to develop drugs that would have all the advantages of AAS, but at the same time the disadvantages of AAS would be reduced to almost zero. Thus the light appeared sarmy (Sarms), which are attached to the receptors selective, selectively stimulate only the growth of muscles, thereby avoiding unwanted side effects.